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GWAS-related eQTLs across different cancer types

We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).



e.g., "STAD"
e.g., "r²>= 0.8"
e.g., "rs2273"
Cancer type
eQTL type
tagSNP
LD
SNP ID
SNP position (hg19)
Gene symbol
Gene position (hg19)
Beta
t-stat
p-value
GWAS-Traits
THCA cis rs12134133 1 rs6658718 chr1:207458906 CD55 chr1:207494817-207534309:+ 0.19 7.71 7.53E-14 Posterior cortical atrophy and Alzheimer's disease
THCA cis rs12748152 1 rs6659176 chr1:27239920 ZDHHC18 chr1:27153201-27182207:+ 0.72 7.46 4.13E-13 HDL cholesterol;Triglycerides;LDL cholesterol
THCA cis rs13191362 1 rs66594243 chr6:163169024 PACRG chr6:163148164-163736523:+ 0.54 7.55 2.17E-13 Body mass index
THCA cis rs7968440 1 rs66597435 chr12:50945269 DIP2B chr12:50898768-51142448:+ 0.12 3.8 0.000164 Fibrinogen
THCA cis rs2421332 1 rs66598018 chr2:61878318 C2orf74 chr2:61372243-61391964:+ 0.24 3.87 0.000122 Homeostasis model assessment of beta-cell function (interaction)
THCA cis rs2292096 1 rs6660197 chr1:200703541 DDX59 chr1:200610119-200639126:- -0.25 -3.82 0.00015 Epilepsy
THCA cis rs12134133 1 rs6660254 chr1:207446091 CD55 chr1:207494817-207534309:+ 0.19 7.63 1.27E-13 Posterior cortical atrophy and Alzheimer's disease
THCA cis rs12134133 1 rs6660557 chr1:207454596 CD55 chr1:207494817-207534309:+ 0.19 7.69 8.48E-14 Posterior cortical atrophy and Alzheimer's disease
THCA cis rs2275426 1 rs6661910 chr1:46290632 CCDC163P chr1:45960581-45965646:- -0.51 -10 1.73E-21 Body mass index
THCA cis rs2275426 1 rs6661910 chr1:46290632 GPBP1L1 chr1:46092978-46152302:- 0.16 4.12 4.55E-5 Body mass index
THCA cis rs2275426 1 rs6661910 chr1:46290632 MMACHC chr1:45965856-45976737:+ -0.2 -4.33 1.83E-5 Body mass index
THCA cis rs2275426 1 rs6661910 chr1:46290632 MUTYH chr1:45794915-45806142:- 0.31 8.37 6.29E-16 Body mass index
THCA cis rs2292096 1 rs6661980 chr1:200830990 DDX59 chr1:200610119-200639126:- -0.22 -3.45 0.000619 Epilepsy
THCA cis rs891378 1 rs6662070 chr1:207505709 CD55 chr1:207494817-207534309:+ 0.15 6.59 1.2E-10 Spherical equivalent (joint main effects and education interaction)
THCA cis rs4332428 1 rs66624122 chr10:4981039 AKR1C2 chr10:4964715-5060207:- 0.32 4.2 3.25E-5 Height